Evidence-minded strength, weight loss, and longevity for men over 50.
I lost 170 pounds, rebuilt in a garage gym, and write about what actually works: lifting, GLP-1s, cardio, sleep, and reading your own bloodwork. No hype, no guru worship.
GLP-1s & Metabolic Health
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Tirzepatide Wins Weight Loss. Semaglutide Has the Hard-Outcome Data.
A BMJ analysis of 262 trials crowned tirzepatide the weight-loss king. But the drug with the hard survival…
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A Yale Team Tried 49 Online GLP-1 Sellers. Forty-Five Prescribed.
A Yale secret-shopper study tried 49 direct-to-consumer GLP-1 sites. 45 wrote a prescription, some in five minutes. What…
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GLP-1 Muscle Loss Scared Me Into the Gym. The Fear Was Overblown.
The GLP-1 muscle loss panic scared me into training at 50. It turned out overblown, but the habit…
Heart & Bloodwork
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The First PCSK9 Cholesterol Pill Was Just Approved. Here’s Who Might Need It
The FDA approved Lipfendra (enlicitide), the first oral PCSK9 inhibitor. What it costs, how the pill compares to…
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VO2 Max Predicts Longevity. Just Not the Way Podcasts Say It Does
The “five times the risk” number is real. The useful lesson for a fifty-year-old is smaller, less sexy,…
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The Cholesterol Expert Who Can’t Take Statins
The most influential cholesterol educator alive can’t tolerate statins or ezetimibe. When he needed the expensive PCSK9 drug,…
Strength & the Rebuild
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Cold Plunges Got the Hype. Saunas Got the Evidence.
Cold plunges get the attention, but the sauna is the one with decades of hard-outcome data. What the…
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VO2 Max Predicts Longevity. Just Not the Way Podcasts Say It Does
The “five times the risk” number is real. The useful lesson for a fifty-year-old is smaller, less sexy,…
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The Strength-Training Number Your Doctor Skips: 90 Minutes a Week
A 147,000-person, 30-year Harvard study gives a rough number for the strength-training half of the exercise guideline: around…
Preventive Health
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Romaine Keeps Making People Sick. I Quit It, and I’m Not Missing Much.
A cyclospora outbreak just sickened 1,645 people across 34 states, and romaine keeps causing E. coli recalls. Is…
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The 2025 Blood Pressure Guidelines Didn’t Change Who Has Hypertension. They Replaced an Outdated Calculator.
The 2025 blood pressure guidelines sound like a shake-up. Here’s what actually changed about who gets medication, and…
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Cold Plunges Got the Hype. Saunas Got the Evidence.
Cold plunges get the attention, but the sauna is the one with decades of hard-outcome data. What the…
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The 170-Pound Rebuild
The food noise went quiet. Then I had to rebuild the rest.
GLP-1 Pipeline Tracker
Every approved and pipeline drug, updated.
Home Gym & Gear
The exact setup I actually use.
The Newsletter
One evidence-minded email each Sunday.