Evidence-minded strength, weight loss, and longevity for men over 50.
I lost 170 pounds, rebuilt in a garage gym, and write about what actually works: lifting, GLP-1s, cardio, sleep, and reading your own bloodwork. No hype, no guru worship.
GLP-1s & Metabolic Health
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Tirzepatide Wins Weight Loss. Semaglutide Has the Hard-Outcome Data.
A BMJ analysis of 262 trials crowned tirzepatide the weight-loss king. But the drug with the hard survival…
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A Yale Team Tried 49 Online GLP-1 Sellers. Forty-Five Prescribed.
A Yale secret-shopper study tried 49 direct-to-consumer GLP-1 sites. 45 wrote a prescription, some in five minutes. What…
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GLP-1 Muscle Loss Scared Me Into the Gym. The Fear Was Overblown.
The GLP-1 muscle loss panic scared me into training at 50. It turned out overblown, but the habit…
Heart & Bloodwork
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VO2 Max Predicts Longevity. Just Not the Way Podcasts Say It Does
The “five times the risk” number is real. The useful lesson for a fifty-year-old is smaller, less sexy,…
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The Cholesterol Expert Who Can’t Take Statins
The most influential cholesterol educator alive can’t tolerate statins or ezetimibe. When he needed the expensive PCSK9 drug,…
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A Single Shot That Cuts Your LDL by 62 Percent. The Catch: It Edits Your DNA.
Eli Lilly’s VERVE-102 gene-editing therapy cut LDL by 62 percent at the highest dose in Phase 1, with…
Strength & the Rebuild
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Cold Plunges Got the Hype. Saunas Got the Evidence.
Cold plunges get the attention, but the sauna is the one with decades of hard-outcome data. What the…
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VO2 Max Predicts Longevity. Just Not the Way Podcasts Say It Does
The “five times the risk” number is real. The useful lesson for a fifty-year-old is smaller, less sexy,…
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The Strength-Training Number Your Doctor Skips: 90 Minutes a Week
A 147,000-person, 30-year Harvard study gives a rough number for the strength-training half of the exercise guideline: around…
Preventive Health
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The 2025 Blood Pressure Guidelines Didn’t Change Who Has Hypertension. They Replaced an Outdated Calculator.
The 2025 blood pressure guidelines sound like a shake-up. Here’s what actually changed about who gets medication, and…
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Cold Plunges Got the Hype. Saunas Got the Evidence.
Cold plunges get the attention, but the sauna is the one with decades of hard-outcome data. What the…
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Obesity’s Blood Pressure and Cholesterol Gap Shrank. It Wasn’t Ozempic.
A million-person Lancet study shows older adults with obesity now match normal-weight peers on blood pressure and cholesterol,…
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The 170-Pound Rebuild
The food noise went quiet. Then I had to rebuild the rest.
GLP-1 Pipeline Tracker
Every approved and pipeline drug, updated.
Home Gym & Gear
The exact setup I actually use.
The Newsletter
One evidence-minded email each Sunday.